The RIKEN BDR Workshop, "Exploring Organoid Design with Microengineering," will be held on Tuesday, February 6, 2024, at the Kobe Campus of the RIKEN Center for Biosystems Dynamics Research (BDR).

The discovery of self-organizational processes within stem cell culture systems has enabled scientists to generate three-dimensional mini-organs known as organoids. We continue to see rapid advances being made in organoid research, which has led to the unveiling of developmental mechanisms, insights into disease pathogenesis, and development of applications for regenerative medicine.

Recently, there has been a global shift to adopt a more engineering-based perspective to organoid research by generating asymmetric cell culture "fields" that mimic in vivo conditions of living organisms using engineering approaches to manipulate and induce the autonomous formation and further complexity of multicellular systems. These engineering approaches are expected to lead to the development of technologies capable of replicating the three-dimensional structures and the intricate interconnections established among multiple organs within the body.

For this workshop, we have invited researchers who are working on cutting-edge research to develop engineering technologies to reconstruct more complex, multicellular and multi-organ systems and functions in vitro, which could not be achieved using conventional culturing methods. We hope that the workshop will serve to deepen our understanding of this emerging field as well as consider the future of organoid engineering research.

Date & Time:	Tuesday, February 6, 2024 (13:00～18:00)
Format:	In-person
Venue:	RIKEN Center for Biosystems Dynamics Research Kobe Campus West Area Auditorium, 1F Developmental Biology Building C 2-2-3, Minatojima-minamimachi, Chuo-ku Kobe, Hyogo 650-0047, Japan (Approximately 5-minute walk from "Iryo Center Station" of the Port Liner train) 　▶ Directions 　▶ Google Map
Language:	English
Participation Fee:	FREE *Banquet fee required separately (optional)
Registration:	Advance registration required from the online registration form Registration Deadline: Tuesday, January 30, 2024
Banquet Fee (optional):	General: 5,000 JPY / Students: 1,000 JPY
Organizers:	Mitsuru Morimoto（Laboratory for Lung Development and Regeneration, RIKEN BDR) Minoru Takasato (Laboratory for Human Organogenesis, RIKEN BDR) Masaya Hagiwara（Human Biomimetic System RIKEN Hakubi Research Team, RIKEN BDR)
Poster:	Download Poster (1.28MB)

*20 minutes presentaion + 10 minutes discussion.

Time	Speakers
Opening Remarks
13:00-13:10	Eisuke Nishida (RIKEN BDR Director)
Session 1 Moderator: Mitsuru Morimoto
13:10-13:40	Designer niche cells to engineer tissue environment Satoshi Toda (Kanazawa University)
13:40-14:10	Hair follicle organoid formation through self-assembly of epithelial and mesenchymal cells Tatsuto Kageyama (Yokohama National University)
14:10-14:40	Elasto-plasticity as a key regulator of the progress of morphogenesis Satoru Okuda (Kanazawa University)
14:40-15:00	Coffee Break
Session 2 Moderator: Masaya Hagiwara
15:00-15:30	Design of vascularized Tissue Models by Mechanoengineering of Cell Microenvironment Michiya Matsusaki (Osaka University)
15:30-16:00	Muscle tissue construction using hollow fiber bioreactor Ai Shima (Tokyo University)
16:00-16:30	Metabolic Analysis in Cancer: Vascularized Organoids on a Chip Approach Yuji Nashimoto (Tokyo Medical and Dental University)
16:30-16:50	Coffee Break
Session 3 Moderator: Minoru Takasato
16:50-17:20	Design and control of in vitro microenvironments to achieve organoid architecture Masaya Hagiwara　(RIKEN BDR)
17:20-17:50	Connecting organoids to build neural circuits Yoshiho Ikeuchi　(Tokyo University)
17:50-18:00	Closing Remarks by Minoru Takasato (RIKEN BDR)
18:00-19:30	Social Gathering

Registration is now CLOSED.

Advance online registration is required for all participants. Registration fee is FREE (Banquet fee required separately / optional).

Click the "Registration" button below to access the online registration form and enter the required information.

If you are from EEA* countries or from UK, please make sure that you read and agree on the “Statement regarding handling personal information based on General Data Protection Regulation (GDPR)” when making your registration. Registration will NOT be completed unless you agree to the statement.

*The EEA (European Economic Area) includes 27 EU countries and Iceland, Liechtenstein, and Norway.

A confirmation e-mail will be sent automatically to your e-mail address. If you do not receive the confirmation e-mail, please contact the secretariat.

Regsitration on the event day

Registration will open at 12:00 on Tuesday, February 6 at the venue.

Registration fee for the workshop is FREE, but if you registered for the banquet, please pay the fee at the registration desk in cash in Japanese YEN.

Internet

Wireless internet connection is available. Please inquire at the registration desk for details.

Banquet

A banquet is scheduled after the scientific program at the workshp venue. We hope that many participants will attend.

Those who wish to attend the banquet must indicate they would like to attend when completing the online registration for the workshop.

Childcare service

Temporary childcare service is available for workshop attendees at a nearby childcare facility jointly operated by RIKEN and other companies. Please contact secretariat by Tuesday, January 9, 2024 if you intend to use the service.

There will be at least 1 staff member on duty, when necessary, who will be able to communicate in English with parents/guardians regarding childcare issues.

・Time Available：8:15 to 18:00 (Extended childcare available until 20:00)

　*In principle, please use the nursery only during the workshop hours.

・Capacity and Fees:

　Age 0 (Up to 2 children): 230 yen/30 minutes

　Age 1 & 2 (Up to 2 children): 220 yen/30 minutes

　Age 3- (Up to 5 children): 170 yen/30 minutes

　*Note that we may not be able to accept children when the capacity is reached.

　*Payment must be made in cash in Japanese yen when you pick up your child. Please prepare exact amount with no change. If the time is extended, extended time will also be charged.

・Management Company: Child Heart Co., Ltd

Conference Rules

- Photography, video recording, and audio recording is prohibited unless otherwise authorized.

- Please do not post any contents of the presentations on social media.

- Please turn your mobile phone to silent mode or turn it off inside the venue.

- Smoking is prohibited on the premises.

Photos

Please note that any photographic images taken by the staff during the workshop may be used on RIKEN’s website or other promotional materials. If there are any inconvenience, please inform the secretariat.

Organoid Project Secretariat

RIKEN Center for Biosystems Dynamics Research (BDR)

2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe 650-0047, Japan

E-mail: bdr-organoid@ml.riken.jp